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Stefan Knackmuss Selected Research

Laminin Receptors

1/2015Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity.
1/2014Anti-LRP/LR specific antibody IgG1-iS18 impedes adhesion and invasion of liver cancer cells.
1/2013Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18.
1/2013In vitro inhibition of angiogenesis by antibodies directed against the 37kDa/67kDa laminin receptor.
5/2012Anti-LRP/LR-specific antibody IgG1-iS18 significantly reduces adhesion and invasion of metastatic lung, cervix, colon and prostate cancer cells.
8/2008Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy.
5/2008Invasion of tumorigenic HT1080 cells is impeded by blocking or downregulating the 37-kDa/67-kDa laminin receptor.
1/2008Single chain Fv antibodies directed against the 37 kDa/67 kDa laminin receptor as therapeutic tools in prion diseases.

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Stefan Knackmuss Research Topics

Disease

9Neoplasms (Cancer)
01/2021 - 05/2008
2Alzheimer Disease (Alzheimer's Disease)
01/2016 - 01/2013
2Neoplasm Metastasis (Metastasis)
01/2015 - 05/2008
2Prion Diseases (Transmissible Spongiform Encephalopathies)
08/2008 - 01/2008
1Squamous Cell Carcinoma of Head and Neck
01/2021
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021
1Colorectal Neoplasms (Colorectal Cancer)
01/2021
1Glioma (Gliomas)
01/2017
1Amyloid Plaque
01/2016
1Body Weight (Weight, Body)
06/2015
1Hodgkin Disease (Hodgkin's Disease)
06/2015
1Liver Neoplasms (Liver Cancer)
01/2014
1Breast Neoplasms (Breast Cancer)
01/2013
1Prostatic Neoplasms (Prostate Cancer)
05/2012
1Lung Neoplasms (Lung Cancer)
05/2012
1Colonic Neoplasms (Colon Cancer)
05/2012
1Uterine Cervical Neoplasms (Cancer of the Cervix)
05/2012
1Neuroendocrine Tumors (Neuroendocrine Tumor)
10/2008
1Scrapie
08/2008
1Nervous System Diseases (Neurological Disorders)
01/2008
1Asthma (Bronchial Asthma)
03/2007

Drug/Important Bio-Agent (IBA)

8Laminin ReceptorsIBA
01/2015 - 01/2008
5AntibodiesIBA
01/2017 - 01/2008
3laminin 1IBA
01/2014 - 05/2012
2ErbB Receptors (EGF Receptor)IBA
01/2021 - 01/2017
2PrionsIBA
08/2008 - 05/2008
2Single-Chain AntibodiesIBA
08/2008 - 01/2008
1Phosphates (Orthophosphate)IBA
01/2021
1Chimeric Antigen ReceptorsIBA
01/2021
1Tyrosine Kinase InhibitorsIBA
01/2021
1Monoclonal AntibodiesIBA
01/2021
1EnzymesIBA
01/2021
1Epidermal Growth Factor (EGF)IBA
01/2021
1Immunoglobulin Fc FragmentsIBA
01/2021
1ImmunosorbentsIBA
01/2021
1epidermal growth factor receptor VIIIIBA
01/2017
1Amyloid (Amyloid Fibrils)IBA
01/2016
1Protein Isoforms (Isoforms)IBA
01/2016
1AFM13IBA
06/2015
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2015
1matrigelIBA
01/2014
1Amyloid beta-PeptidesIBA
01/2013
1Peptides (Polypeptides)IBA
10/2008
1Radioisotopes (Radionuclides)IBA
10/2008
1Polysaccharides (Glycans)IBA
05/2008
1Indicators and Reagents (Reagents)IBA
05/2008
1Messenger RNA (mRNA)IBA
05/2008
1Laminin (Merosin)IBA
05/2008
1Prion ProteinsIBA
01/2008
1CytokinesIBA
03/2007
1Interleukin-13IBA
03/2007

Therapy/Procedure

3Therapeutics
01/2021 - 05/2008
2Immunotherapy
01/2017 - 06/2015